Effects of vardenafil administration on intravaginal ejaculatory latency time in men with lifelong premature ejaculation
نویسندگان
چکیده
منابع مشابه
Peripheral Arterial Tonometry to Measure the Effects of Vardenafil on Sympathetic Tone in Men with Lifelong Premature Ejaculation
To elucidate whether adrenergic overtone is involved in the pathophysiology of men with lifelong (LL) premature ejaculation (PE), we investigated differences in reactive hyperemia index (RHI) responses by using peripheral arterial tonometry (PAT). 20 men with LL-PE (18-40 years) were enrolled in an 8-week, double-blind, placebo-controlled, crossover study and compared with 10 age-matched contro...
متن کاملThe 5-HT2C receptor gene Cys23Ser polymorphism influences the intravaginal ejaculation latency time in Dutch Caucasian men with lifelong premature ejaculation
It has been postulated that the persistent short intravaginal ejaculation latency time (IELT) of men with lifelong premature ejaculation (LPE) is related to 5-hydroxytryptamine (HT)2C receptor functioning. The aim of this study was to investigate the relationship of Cys23Ser 5-HT2C receptor gene polymorphism and the duration of IELT in men with LPE. Therefore, a prospective study was conducted ...
متن کاملThe mathematical formula of the intravaginal ejaculation latency time (IELT) distribution of lifelong premature ejaculation differs from the IELT distribution formula of men in the general male population
PURPOSE To find the most accurate mathematical description of the intravaginal ejaculation latency time (IELT) distribution in the general male population. MATERIALS AND METHODS We compared the fitness of various well-known mathematical distributions with the IELT distribution of two previously published stopwatch studies of the Caucasian general male population and a stopwatch study of Dutch...
متن کاملGene mapping of serotoninergic system polymorphisms provides insight on pathology and treatment of men with lifelong premature ejaculation
We appreciate and thank Drs Saitz and Serefoglu for their positive and sympathetic words on our article.1 Indeed, our genetic studies have shown that 5‐HTTLPR polymorphism, 5‐HT1A receptor gene polymorphism and 5‐HT2C receptor gene polymorphism are associated with the duration of the intravaginal ejaculatory latency time in men with lifelong premature ejaculation. In line with the remarks,1 we ...
متن کاملThe pathophysiology of lifelong premature ejaculation
For many decades it has been thought that lifelong premature ejaculation (PE) is only characterized by persistent early ejaculations. Despite enormous progress of in vivo animal research, and neurobiological, genetic and pharmacological research in men with lifelong PE, our current understanding of the mechanisms behind early ejaculations is far from complete. The new classification of PE into ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: International Journal of Impotence Research
سال: 2009
ISSN: 0955-9930,1476-5489
DOI: 10.1038/ijir.2009.21